Perception of the patient with type 2 Diabetes Mellitus regarding the use of insulin and its adverse events: integrative review

Authors

  • Cárita Luene Da Silva Centro Universitário Barão de Mauá. Unidade Central. Curso de Enfermagem. Endereço: Rua Ramos de Azevedo, nº 423 Jd. Paulista - Ribeirão Preto/SP , CEP: 14.090-180 http://orcid.org/0009-0000-4434-5893
  • Claudia Tatiana Raymundo Centro Universitário Barão de Mauá. Unidade Central. Curso de Enfermagem. Endereço: Rua Ramos de Azevedo, nº 423 Jd. Paulista - Ribeirão Preto/SP , CEP: 14.090-180 http://orcid.org/0009-0009-9494-5286
  • Fabiana Coelho Inouye Universidade de São Paulo. Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Departamento de Ciências Farmacêuticas Endereço: Av. do Café, s/n, Vila Monte Alegre, Ribeirão Preto - SP, Brasil, CEP: 14040-900 http://orcid.org/0000-0002-2980-7014
  • Tania Aparecida Cancian Masella Centro Universitário Barão de Mauá. Unidade Central. Curso de Enfermagem. Endereço: Rua Ramos de Azevedo, nº 423 Jd. Paulista - Ribeirão Preto/SP , CEP: 14.090-180 http://orcid.org/0000-0002-8195-8434
  • Juliana Pereira Machado Centro Universitário Barão de Mauá. Unidade Central. Curso de Enfermagem. Endereço: Rua Ramos de Azevedo, nº 423 Jd. Paulista - Ribeirão Preto/SP , CEP: 14.090-180 http://orcid.org/0000-0003-2225-8355
  • Maria Olívia Barboza Zanetti Universidade de São Paulo. Escola de Enfermagem de Ribeirão Preto da Universidade de São Paulo. Departamento de Enfermagem Psiquiátrica e Ciências Humanas. Endereço: Rua Prof. Hélio Lourenço, 3900 - Vila Monte Alegre, Ribeirão Preto - SP, CEP: 14040-902 http://orcid.org/0000-0002-9551-4711

DOI:

https://doi.org/10.14450/2318-9312.v36.e1.a2024.pp78-92

Keywords:

Diabetes Mellitus, Insulin, Attitude to Health

Abstract

Type 2 Diabetes Mellitus (DM2) is a significant public health problem that negatively affects the quality
and life expectancy of the patient and overburdens the health system. There is a considerable demand
for patients with DM2 seeking medical care, especially those who present symptoms of hypoglycemia,
often caused by inadequate use of insulin. The objective was to identify difficulties related to insulin use
in people with DM2. An integrative literature review was carried out and searches were carried out in
the PubMed, LILACS and EMBASE databases, resulting in 280 publications. Screening was done with
the Rayyan application and, after removing duplicates and critically analyzing titles and abstracts, 17
articles were selected for full reading. Finally, 8 publications were included in the study and analyzed
for pattern and theme identification. This review found difficulties for patients in managing the disease,
including insufficient knowledge about the disease and insulin. The main barriers to insulin use reported
were discomfort during application; belief that the disease is not serious; lifestyle restrictions; negative
social stigma; insecurity in handling and applying insulin; difficulties in transport, storage and disposal.
The low number of articles indicates that this topic needs further exploration to reformulate health policies
and programs.

Published

2025-12-19

How to Cite

Da Silva, C. L., Raymundo, C. T., Inouye, F. C., Cancian Masella, T. A., Machado, J. P., & Zanetti, M. O. B. (2025). Perception of the patient with type 2 Diabetes Mellitus regarding the use of insulin and its adverse events: integrative review. Infarma - Pharmaceutical Sciences, 36(1), 78–92. https://doi.org/10.14450/2318-9312.v36.e1.a2024.pp78-92

Issue

Section

Review Article

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