PHARMACEUTICAL CARE FOR OLDER ADULTS WITH ALZHEIMER’S DISEASE: CLINICAL APPROACH AND PHARMACOLOGICAL INTERVENTIONS
DOI:
https://doi.org/10.14450/infarma.e202618Keywords:
Pharmacist, ALZHEIMER´´'S, DRUGSAbstract
To analyze the importance of pharmacists in the therapeutic management of individuals with Alzheimer’s disease. This is a descriptive narrative review of the literature, employing both qualitative and quantitative approaches, which included articles published between 2012 and 2020, selected through searches of national and international databases such as MEDLINE/PubMed, SciELO, BVS, and LILACS. Alzheimer’s disease is caused by the accumulation of amyloid and tau proteins in the brain, which damages neurons and compromises the cholinergic system, leading to cognitive and functional decline and memory loss in patients. The diagnosis is predominantly clinical, established by ruling out other conditions, with the aid of cognitive tests and complementary examinations. The clinical management of Alzheimer’s disease is symptomatic, supported by pharmacological therapy with acetylcholinesterase inhibitors and memantine, which are provided by the SUS (Brazilian Unified Health System) in accordance with the Therapeutic Guidelines. In this context, pharmaceutical care has established itself as an indispensable tool for ensuring treatment adherence, mitigating medication-related risks, and optimizing the quality of life for patients and their families. Pharmacists play a crucial role in the management of Alzheimer’s disease (AD), ensuring treatment adherence and effectiveness within a multidisciplinary setting. Promising studies highlight immunomodulators as a therapeutic alternative against the progression of AD; however, the toxicity of these agents limits their use. Therefore, the pharmacist’s role is essential for monitoring safety, optimizing therapy, and reducing risks, thereby ensuring better clinical outcomes.
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Copyright (c) 2026 Phablicy Helorrayne Freitas Menezes , Ana Carolina Dias da Silva, Natalle do Socorro da Costa Freitas, Luann Wendel Pereira de Sena, Amanda Gabryelle Nunes Cardoso Mello
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